Wednesday, March 30, 2016

5-Star Rated Lab Homogenizer

The Bio-Gen PRO200 is a 5-star rated homogenizer



FEATURES

  • Tissue homogenizer / small sample hand homogenizer
  • Hand-held or Post-mounted laboratory homogenizer unit
  • Small and powerful, 144 W
  • Ideal for processing within various tube sizes from 0.5ml to small beakers
  • Variable speed from 5,000 to 35,000 RPM
  • Separate ON/OFF switch 
  • Quiet
  • 2 Year Warranty
  • Generator probes and accessories sold separately 

Monday, March 28, 2016

Multi-Prep: Feature Homogenizer

Check out the Labcompare featured homogenizer.



Multi-Prep Rapid Homogenizer System

FEATURES
  • Rapid automated multi-sample homogenizing
  • Process up to 6 samples at a time
  • Samples homogenized in seconds
  • Store up to 10 different programs
  • Easy Load Spider Tube Racks
  • Accommodates standard tubes from 5ml to 50ml*
  • Can perform 60 oscillations per minute
  • Automated engagement & disengagement of Probes
  • Multi-Prep Probes ensure great results while avoiding cross contamination
  • Compact design, occupies small footprint

*Depends on tube dimensional size

Wednesday, March 23, 2016

Will homogenizing affect my steeping time?



We have been working closely with many customers lately in regards to these specific type of applications.  From some of our customers processing smaller volumes (10-50ml), we have been told that 15 seconds of homogenization is like a week or two of steeping.   Our homogenizers are high shear homogenizers which create a uniform particle bandwith of your sample.  This is different than a traditional blender.  Blending isn't the same as homogenizing and it would definitely take a lot longer.  It has been reported that  15-30 seconds of a homogenizer would be equivalent to what might be accomplished by a blender in 20 minutes.   The benefit of our equipment is there is minimal to no heat produced during processing.


Request a Quote

Tuesday, March 22, 2016

Homogenizing from A - Z Post #4

Homogenizing A - Z 


Homogenizing is one of the first steps in research and PRO homogenizers have been used to process so many different type of samples from A (acetate) to Z (zebrasfish).

What can we help you homogenize today?
Take a look at our extensive homogenizing application database

Or review letters H & I here: 

Hair shampoo
PRODUCT APPLICATION REPORT
MATERIAL:Hair shampoo
VOLUME OF MATERIAL:15000-20000g
MEDIUM:None
VOLUME OF MEDIUM:None
PROCESS:Mix shampoo to desired consistency
PREVIOUS OR CURRENT METHOD:Large mixer with 24" rotor and
4" blade
EQUIPMENT USED:PRO250 Homogenizer w/stand & 20mm probe or PRO300 Homogenizer with PRO Safety Sealed Chamber Assembly
APPLICATION AND RESULTS:The blade moved a great deal of the
shampoo because the high rpms.


Hamster brain
PRODUCT APPLICATION REPORT
MATERIAL:Hamster brain
VOLUME OF MATERIAL:10 ml
MEDIUM:Not reported
VOLUME OF MEDIUM:Not reported
PROCESS:Homogenization for RNA and protein purification
analysis
PREVIOUS OR CURRENT METHOD:Not reported
EQUIPMENT USED:PRO200 Homogenizer with 10mm generator
APPLICATION AND RESULTS:Successful completion of application.


Hamster tissue
PRODUCT APPLICATION REPORT
MATERIAL:Hamster tissue
VOLUME OF MATERIAL:9 grams
MEDIUM:Aqueous
VOLUME OF MEDIUM:1-5 ml
PROCESS:Release bacteria from tissue
PREVIOUS OR CURRENT METHOD:None
EQUIPMENT USED:PRO200 Homogenizer with 10mm generator
APPLICATION AND RESULTS:Required results achieved easily.


Heart cells
PRODUCT APPLICATION REPORT
MATERIAL:Heart cells
VOLUME OF MATERIAL:Not reported
MEDIUM:Not reported
VOLUME OF MEDIUM:Not reported
PROCESS:Isolation of metabolites
PREVIOUS OR CURRENT METHOD:None
EQUIPMENT USED:PRO200 Homogenizer with 5mm generator
APPLICATION AND RESULTS:Worked well. Intended results achieved
within seconds.


Hippocampus
PRODUCT APPLICATION REPORT
MATERIAL:Rat hippocampus
VOLUME OF MATERIAL:Not reported
MEDIUM:Cocktail lysis buffer containing protease
inhibitors and phosphatase inhibitors
VOLUME OF MEDIUM:Not reported
PROCESS:Snap-frozen in liquid nitrogen and homogenized
PREVIOUS OR CURRENT METHOD:Not reported
EQUIPMENT USED:PRO200 Homogenizer 
APPLICATION AND RESULTS:
DOI:
Achieved desired homogenization results
http://dx.doi.org/10.1016/j.neuropharm.2014.10.011



Hippocampus and prefrontal cortex 
PRODUCT APPLICATION REPORT
MATERIAL:Hippocampus and prefrontal cortex 
VOLUME OF MATERIAL:1 ml
MEDIUM:
VOLUME OF MEDIUM:Not reported
PROCESS:
PREVIOUS OR CURRENT METHOD:None
EQUIPMENT USED:PRO Homogenizer
APPLICATION AND RESULTS:

DOI:
Hippocampus and prefrontol cortex and
1.0ml for nucleus accumbens, using a handheld homogenizer on slow setting.
http://dx.doi.org/10.1007/s00216-013-7514-9


HIV Infected H9 cells
PRODUCT APPLICATION REPORT
MATERIAL:HIV Infected H9 cells
VOLUME OF MATERIAL:20-200 g
MEDIUM:Not reported
VOLUME OF MEDIUM:50-400 ml
PROCESS:Disrupt cell membrane
PREVIOUS OR CURRENT METHOD:Dounce Homogenizer
EQUIPMENT USED:PRO250 Homogenizer (w/ stand) or PRO300 D Homogenizer with blade and sealed chamber assembly
APPLICATION AND RESULTS:Worked well and sealed system is a
must. However, sharpened blades may pose a huge health risk if
poked into skin.

RECOMMENDATIONS: As an added safety feature for working with a
such material, we would suggest the use of a generator system
(smooth bottomed) that has no exposed sharp edges that can break
the skin of its user.


Human liver
PRODUCT APPLICATION REPORT
MATERIAL:Human liver
VOLUME OF MATERIAL:100-200 ml
MEDIUM:Water
VOLUME OF MEDIUM:Not reported
PROCESS:Complete homogenization
PREVIOUS OR CURRENT METHOD:None
EQUIPMENT USED:PRO250 Homogenizer (w/ stand) or PRO300 D Homogenizer with blade and blade and probe sealed chamber assembly and 20mm probe 
APPLICATION AND RESULTS:Worked best with the blade and sealed
chamber assembly. Chunks were too big for the 20mm generator.


Human tissue
PRODUCT APPLICATION REPORT
MATERIAL:Human tissue
VOLUME OF MATERIAL:5 g
MEDIUM:Not reported
VOLUME OF MEDIUM:Not reported
PROCESS:Homogenization
PREVIOUS OR CURRENT METHOD:Brinkmannn homogenizer
EQUIPMENT USED:PRO200 Homogenizer with 10mm generator
APPLICATION AND RESULTS:Homogenized tissue well and was quieter
than previous methods.


Human tissue
PRODUCT APPLICATION REPORT
MATERIAL:Human tissue
VOLUME OF MATERIAL:.05 ml
MEDIUM:Not reported
VOLUME OF MEDIUM:Not reported
PROCESS:Homogenize RNA
PREVIOUS OR CURRENT METHOD:Not reported
EQUIPMENT USED:PRO200 Homogenizer with 5mm generator
APPLICATION AND RESULTS:Worked well


Human tissue
PRODUCT APPLICATION REPORT
MATERIAL:Human tissue
VOLUME OF MATERIAL:8 ml
MEDIUM:Not reported
VOLUME OF MEDIUM:Not reported
PROCESS:RNA extraction
PREVIOUS OR CURRENT METHOD:Brinkmannn Polytron
EQUIPMENT USED:PRO200 Homogenizer with 7mm generator
APPLICATION AND RESULTS:Liked low noise level of units. Achieved
desired results.


Human tissue
PRODUCT APPLICATION REPORT
MATERIAL:Human tissue
VOLUME OF MATERIAL:20 ml
MEDIUM:Phosphate buffer
VOLUME OF MEDIUM:50 ml
PROCESS:Complete homogenization
PREVIOUS OR CURRENT METHOD:shift blender, mortar and pestle
EQUIPMENT USED:PRO200 Homogenizer with 10mm generator
APPLICATION AND RESULTS:Worked very well and desired results were
achieved.


Intestinal Samples (Swine)
PRODUCT APPLICATION REPORT


MATERIAL:Intestinal samples (Swine)
VOLUME OF MATERIAL:2mm pieces
MEDIUM:
VOLUME OF MEDIUM:
PROCESS:Lysed
PREVIOUS OR CURRENT METHOD:
EQUIPMENT USED:PRO200 Homogenizer
APPLICATION AND RESULTS:


DOI:
To obtain representative measurements from the
2-cm jejunal samples, three cross-sections of
approximately 
2 mm were pooled and lysed using
PRO 200 Post-Mounted Laboratory

http://dx.doi.org/10.1371/journal.pone.0079343




Request a Quote

Friday, March 18, 2016

03/18/16 - PRO Scientific Homogenizers peer reviewed news

We are so proud to be a part of our customer's valuable research. 

Look at all of our customer's new peer reviewed research!  
Thanks for making PRO Scientific a part of your valuable research.  And remember, the DPS-20 Two-Step Homogenizing System can help you simplify your homogenization by combining mechanical AND utlrasonic homogenization into one time saving automate homogenizing system!





Our customers have been really busy!
Here is where PRO Homogenizers are being referenced this week, take a look...

Cartilage powder
· Cartilage powder was susepended in distilled water using a PRO260 homogenizer (new model PRO250C with digital speed control or PR025D) 
·                       PRO250 Homogenizer
·                       PR25D Homogenizer

Hippocampal tissue
· Tissues were homogenizes using a Bio-Gen PRO200 Homogenizer in a lysis buffer
·                       PRO200 Homogenizer         


Japanese medaka
· Tissues were homogenizes in TRI Reagent using a PRO200 homogenizer 
·                       PRO200 Homogenizer       
Journal of Comparative Physiology

Mice brain 
· The brains were then homogenized (using a PRO200 homogenizer) at 24,000 rpm for 2 min in ice-cold PBS
·                       PRO200 Homogenizer       
Mice cardiac tissue 
· The samples were homogenized in TRI reagent...using a PRO200 homogenizer...to extraxt total RNA
·                       PRO200 Homogenizer       
Mice skeletal muscle 
· 50mg gastocnemius muscle was dissected and homogenized in buffer....using a PRO200 homogenizer 
· This research would have benefited from using a DPS-20 which first mechanically homogenizes the sample and then processes the same sample ultrasonically
·                       PRO200 Homogenizer       
·                       DPS-20 Two-Step Homogenizing System
Nature, Scientific Reports

SME micelles 
· SME micelles were fabricated using a homogenization/sonication technique to determine the physiochemical properties
· This research would have benefited from using a DPS-20 which first mechanically homogenizes the sample and then processes the same sample ultrasonically
·                       PRO250 Homogenizer
·                       PR25D Homogenizer   
·                       DPS-20 Two-Step Homogenizing System


Request a Quote

Wednesday, March 16, 2016

Introducing the PRO25D, Powerful, Digital Laboratory Homogenizer

PRO25D Homogenizer


FEATURES

  • Compact digital unit with high watt motor 
  • 0.05ml - 3.5 L volume range and viscosity up to 50,000 mPas
  • Can be used with different PRO Quick Connect Generator Probes, 5mm-30mm diameter
  • Smooth operation and control
  • Can homogenize, emulsify, blend and/or mix
  • Includes U-shape post mounted stand assembly
  • Bright LED display and user-friendly controls
  • Made in the USA with a 2-year warranty 

DESCRIPTION

The NEW PRO25D Homogenizer has a large volume range with processing capability up to 3.5 Liters*.  A digital display & speed control provide the ability to fine-tune speeds between 0 to 30,000 RPM.  Its 3-Turn speed adjust allows precise RPM control in the hundreds.

The versatile and powerful PRO25D Homogenizer is ideal for a wide range of lab applications, including but not limited to compounding, emulsions and suspensions, cell disruption, protein extractions, medical research or pharmaceutical processing. 

*Higher volumes dependent on viscosity.



Request a Quote