Thursday, November 7, 2013

PCR Homogenizer

PRO Homogenizers are ideal for PCR Sample Preparation and RNA/DNA isolation

PCR Homogenizer
PCR is used regularly in all areas of science, including molecular biology, clinical diagnostics, forensic science, environmental science and food science.  When it comes to PCR sample preparation and isolation of RNA, DNA, and proteins, PRO Scientific rotor stator homogenizers are an ideal physical method used to disrupt the sample in both soft and tough tissues.  
Our standard PRO rotor-stator homogenizer generator probes are precision crafted with a very narrow clearance between the inner rotating shaft and outer tube/chamber.  This allows for quick, effective and repetitive processing, meaning you will get the results you want each and every time. 
And the variable speed of our homogenizers allows for the utmost control of your homogenization to ensure a high yield and fragment size. 
When the concern of preventing cross-contamination between samples arises, our multi-sample homogenizing systems such as the Multi-Gen 7XL, DPS-20 and Multi-Prep ensure sample purity while still being compatible with various reagents on the market.  
Regardless of which PRO homogenizer setup is selected, most homogenization can be completed in a matter of seconds which eliminates heat production and ensures preservation of the sample.


Here are just some of the many application references of PCR sample preparation with a PRO Scientific Homogenizer:



Multi-Sample PCR Homogenizing Kit

The Multi-Gen 7XL Homogenizing Package is the perfect PCR Homogenizing Kit.
Multi-Sample PCR Homogenizing
  • Perfect for homogenizing all types of samples, soft to the toughest 
  • Homogenize in microtubes to 50ml tubes
  • 7mm open-slotted tooth design 
  • Without risk of cross contamination and cleaning in between samples
  • Cost effective over plastic disposable generator probes
  • Sterilize by any cleaning method

See our Multi-Sample PCR Homogenizing Kit in Action:


Tissue Homogenizer

Tissue Homogenizer


PRO Homogenizers are ideal tissue tearor homogenizers.
  • PRO Generators probes are precision crafted with a very narrow clearance between the inner rotating shaft and outer tube/chamber. This allows for quick, effective and repetitive homogenizing, meaning you will get the results you want each and every time.
  • The variable speed of our tissue homogenizers allows for maximum homogenization or if necessary for the preservation of organelles, large molecules, and viruses.
  • Most homogenization can be completed in a matter of seconds which eliminates heat production and ensures preservation of the sample.



Here are just some of the many application references of tissue homogenizing with a PRO Scientific Homogenizer:






 Bio-Gen PRO200 Tissue HomogenizerBio-Gen PRO200 for micro-sample tissue homogenizing.
PRO250 High Powered Tissue Homogenizer PRO250 for large volume tissue homogenizing.

Multi-Gen 7XL Multi-Sample Tissue HomogenizerConcerned about cross-contamination between your tissue homogenizing - try the Multi-Gen 7XL Homogenizing Package.

Thursday, October 10, 2013

PRO Deflector Head Accessories for Homogenizer Generator Probes

Enhance Sample Movement for Improved Homogenization

PRO Scientific deflector heads are specifically designed to enhance the homogenization of larger volume and higher viscosisty materials such as creams, lotions, oils, gels and much more.  They are used regularly by cosmetic, nutrition, paint and oil companies.
PRO Deflector Head
The deflector head design creates vertical movement of heavy materials which would otherwise stand stagnant, and promotes increased flow on larger volume samples.
Deflector Head Sample Movement
When processing viscous materials, such as creams and lotions, the PRO deflector head forces materials from the generator tip up its tapered walls, creating increased vertical movement of the entire sample.  The material is then repeatedly cycled back down to the bottom of the container and up through the deflector head until a homogenous mixture is achieved.  
PRO deflector heads mount easily on PRO geneator probes.  Deflector heads are available in acetyl resin and stainless steel and fit generator probes 20mm in diameter and larger.  

Here are just some of the many application references for homogenizing viscous samples with a PRO Scientific Homogenizer:




Wednesday, September 25, 2013

Potter-Elvehjem Grinding Chambers and Pestles vs. PRO Scientific Homogenizer

Potter-Elvehjem Grinding Chambers and Pestles vs. PRO Scientific Homogenizer


Potter-Elvehjem Grinding Chamber vs. 
With a Tissue Grinder Potter-Elvehjem, the PTFE pestle is attached to a stainless steel shaft and homogenization occurs as the sample and buffer are forced through the cylindrical portion of the mortar as the pestle rotates downward.  Generally this is a hand-held process since all movement is done by hand. Using a Potter-Elvehjem homogenizer with a PTFE pestle is a viable option for disrupting cells.  However, it is not very efficient at homogenizing solid tissue.
However, you need not be limited to using only a Tissue Grinder Potter-Elvehjem with your soft tissue samples, such as liver or brain.  A PRO Scientific rotor-stator homogenizer can be an effective means of homogenizing soft tissues.  When using a rotor-stator homogenizer, like PRO Scientific’s homogenizer, it is important to select a generator probe that provides a low sheer number.  With that generator probe selected, most homogenization will take place in a matter of seconds, so heat production is not a concern.


 


Examples of PRO Scientific Homogenizers being used to homogenize soft tissue samples:





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Friday, September 20, 2013

Standard, Deluxe or Premium Micro-Homogenizing Package. Which is right for you?


Microtube Homogenizer

Standard Micro-Homogenizer Package


Micro-Sample Homogenizing

  • Fits into 0.5ml, 1.5ml, and 2ml microtubes
  • Volumes as small as 0.03ml can be easily processed in a matter of seconds
  •  5mm flat-bottom generator probe designed for liquid and soft samples


Deluxe Micro-Homogenizer Package


Micro-Sample Homogenizing

  • Volumes as small as 0.03ml can be easily processed in a matter of seconds
  • 5mm flat-bottom generator  probe designed for liquid and soft samples
  • 7mm saw-tooth generator probe provides faster and extra cutting action
  • Fits into 0.5ml tubes as well as the conical tip of 1.5ml tubes and bottom of 2ml tubes

Premium Micro-Homogenizer Package


Micro-Sample Homogenizing

  • Stand Assembly for hands free homogenizing
  • Fits into 0.5ml tubes as well as the conical tip of 1.5ml tubes and bottom of 2ml tubes
  • Volumes as small as 0.03ml can be easily processed in a matter of seconds
  • 5mm flat-bottom generator  probe designed for liquid and soft samples
  • 7mm saw-tooth generator probe provides faster and extra cutting action

Choosing a homogenizer

How to select a homogenizer package that best suits your needs.

Homogenizer selection guide: Wet or dry sample | Sample size | Generator width | Configuration |  Speed and particle reduction
Need more help selecting a homogenizer package?

PRO Homogenizers versus some of the "cheaper options" homogenizer options
Homogenizer or bead-mill what's the difference and why do you need a PRO Homogenizer
Do you want plastic disposable homogenizer generator probes? Our Multi-Gen systems are the better alternative


APPLICATIONS


PDF DOCUMENTS



Do you want to demo a  PRO Homogenizer before you make any decisions?

Just submit a contact us form or give us a call (P#800-584-3776) and we can help!


Thursday, September 12, 2013

Follow PRO Scientific

Connect with PRO Scientific 


We've had a lot of exciting changes here at PRO Scientific lately.  We've been putting a lot of time into our new website.
As well as our social media platforms, including; LinkedIn, Facebook, Twitter, Blogger and YouTube.  So come check it all out and make sure to follow us, because new information is coming all the time!